High-containment facilities and the role they play in global health security

Biological threats, whether naturally occurring or accidentally or deliberately released, have the potential to endanger lives and disrupt economies worldwide. Thus, high-containment protective measures should be implemented when handling bio-agents that can cause serious, highly contagious diseases, otherwise devastating pandemics can occur. In the fields of scientific investigation, healthcare, and product development, high-containment facilities play a critical role in preventing, detecting, and responding promptly and effectively to threats to global health security. In this paper, we present a summary of the main types of high-containment facilities, as well as their applications, challenges, and suggestions for the future.